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Tangential Flow Filtration


All of our SciLog® TFF systems feature the same software throughout the range ensuring successful process scale-up from laboratory-scale PureTec to pilot-scale SciFlex TFF to GMP-ready SciPure TFF. The systems can be used with cassette or hollow fibre filters and in microfiltration or ultrafiltration applications. Control is enabled by the incorporation of our single-use SciPresSciTemp and SciCon sensors into manifolds for pressure, temperature and conductivity monitoring respectively. 


The PROPOR TFF cross-flow filter range allows Parker domnick hunter to supply your complete TFF solution. The PROPOR TFF range features products for both microfiltration and ultrafiltration applications. The unique modified polyethersulphone (PES) membrane minimizes fouling to give superior flux and throughput performance to reduce processing costs and maximize yields. The filters are available in a standard reusable format, a single-use format that requires no pre-flushing and an autoclaveable version ideal for cell retention application enabling continuous cell culturing. 


Tangential flow filtration operations are also supported by our customizable, single-use overmolded manifolds and our PROPOR SG and PROPOR HC filters for the sterilization of buffer and product streams entering and exiting the unit operation.

Products for Tangential Flow Filtration